Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | POLQ | O75417 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | TACR1 | P25103 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.39 |
| ▸ | PTGIR | P43119 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TDP2 | O95551 | 1/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29002632 | 0.80 | CHRM2 (0.48) | KMT2AMEN1CHRM2CHRM3KDM4E | |
| SCHEMBL31453592 | 0.78 | ALDH1A1 (0.40) | ALDH1A1POLQTACR1PTGIRSLC6A4 | |
| SCHEMBL30638957 | 0.76 | ALDH1A1 (0.51) | ALDH1A1POLQKMT2AMEN1TSHR | |
| SCHEMBL8627403 | 0.74 | TACR1 (0.38) | ALDH1A1POLQKMT2ATACR1CHRM3 | |
| SCHEMBL8624620 | 0.74 | TACR1 (0.38) | ALDH1A1POLQKMT2ATACR1CHRM3 | |
| SCHEMBL9847843 | 0.74 | LMNA (0.38) | ALDH1A1KMT2AMEN1TAS1R3TAS1R1 | |
| SCHEMBL9847880 | 0.73 | GPR174 (0.45) | ALDH1A1KDM4EMAPT | |
| SCHEMBL10528043 | 0.73 | LMNA (0.43) | ALDH1A1POLQCHRM2CHRM3KDM4E | |
| SCHEMBL9302078 | 0.72 | ALDH1A1 (0.48) | ALDH1A1POLQKMT2AMEN1TSHR | |
| SCHEMBL30638964 | 0.72 | ALDH1A1 (0.45) | ALDH1A1POLQKMT2AMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0430847-A1 | Procedure for the preparation of N-cyclopropyl-4-fluoroanilines | CENTRO MARGA PARA LA INVESTIGACION S.A. (ES) | 1991-06-05 | — | — | EP | disclosed |