SCHEMBL9847889

SCHEMBL9847889

Fc1ccc(F)c(Cl)c1Cl

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TNF P01375 1/20 0.46
RIPK1 Q13546 1/20 0.46
LMNA P02545 2/20 0.43
CYP2A6 P11509 1/20 0.43
HTR2A P28223 4/20 0.41
HTR2C P28335 4/20 0.41
HTR2B P41595 2/20 0.41
DAO P14920 1/20 0.35
TSHR P16473 4/20 0.35
HDAC8 Q9BY41 1/20 0.35
ALDH1A1 P00352 2/20 0.33
MEN1 O00255 1/20 0.32
MAPT P10636 1/20 0.32
HTT P42858 1/20 0.32
KMT2A Q03164 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
NFE2L2 Q16236 1/20 0.32
MAPK1 P28482 2/20 0.32
HIF1A Q16665 2/20 0.32
TDP1 Q9NUW8 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1756515 0.87 CYP3A4 (0.46) TNFRIPK1LMNACYP2A6HTR2A
SCHEMBL31242522 0.87 CYP3A4 (0.46) TNFRIPK1LMNACYP2A6HTR2A
SCHEMBL31289362 0.82 TNF (0.41) TNFRIPK1LMNACYP2A6HTR2A
SCHEMBL2046247 0.82 TNF (0.41) TNFRIPK1LMNACYP2A6HTR2A
SCHEMBL31066559 0.82 ALDH1A1 (0.42) TNFRIPK1HTR2AHTR2CHTR2B
SCHEMBL3087235 0.82 TNF (0.37) TNFRIPK1LMNACYP2A6HTR2A
SCHEMBL29616362 0.82 TNF (0.37) TNFRIPK1LMNACYP2A6HTR2A
SCHEMBL911410 0.82 CYP3A4 (0.55) TNFRIPK1LMNADAOTSHR
SCHEMBL12479120 0.82 NOTUM (0.43) TNFRIPK1LMNACYP2A6HTR2A
SCHEMBL2578269 0.82 ACHE (0.38) TNFRIPK1LMNACYP2A6HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4719022-A2 NITROGEN-CONTAINING HETEROCYCLES FOR ORGANIC ELECTROLUMINESCENT DEVICES UDC Ireland Limited (IE) 2026-04-01 EP disclosed
US-20250185505-A1 NITROGENOUS HETEROCYCLES FOR ORGANIC ELECTROLUMINESCENT DEVICES UDC IRELAND LIMITED (IE) 2025-06-05 US disclosed
US-20250171684-A1 AROMATIC HETREOCYCLES FOR ORGANIC ELECTROLUMINESCENT DEVICES UDC IRELAND LIMITED (IE) 2025-05-29 US disclosed
WO-2023161167-A1 NITROGENOUS HETEROCYCLES FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2023-08-31 WO disclosed
WO-2020022378-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE 出光興産株式会社 2020-01-30 WO disclosed
EP-0430847-A1 Procedure for the preparation of N-cyclopropyl-4-fluoroanilines CENTRO MARGA PARA LA INVESTIGACION S.A. (ES) 1991-06-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250171684-A1 AROMATIC HETREOCYCLES FOR ORGANIC ELECTROLUMINESCENT DEVICES AHR, PAH, DDT TNF 4749/4885RIPK1 4516/4885LMNA 3236/4885
US-20250185505-A1 NITROGENOUS HETEROCYCLES FOR ORGANIC ELECTROLUMINESCENT DEVICES NES, NUDC, HCN2 TNF 4681/4885RIPK1 2399/4885LMNA 2890/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.