Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.47 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.46 |
| ▸ | MDM4 | O15151 | 1/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.46 |
| ▸ | ERAP2 | Q6P179 | 3/20 | 0.44 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6826832 | 0.83 | NPSR1 (0.53) | ESR1ESR2CNR1CNR2TSHR | |
| SCHEMBL8008631 | 0.83 | NPSR1 (0.53) | ESR1ESR2CNR1CNR2TSHR | |
| SCHEMBL1721283 | 0.83 | NPSR1 (0.53) | ESR1ESR2CNR1CNR2TSHR | |
| SCHEMBL7456029 | 0.82 | ESR1 (0.54) | ESR1ESR2CNR1CNR2TSHR | |
| SCHEMBL7456024 | 0.82 | ESR1 (0.54) | ESR1ESR2CNR1CNR2TSHR | |
| SCHEMBL27723176 | 0.80 | ESR1 (0.51) | ESR1ESR2CNR1CNR2TSHR | |
| SCHEMBL7237658 | 0.79 | ESR1 (0.59) | ESR1ESR2TSHRNPSR1KMT2A | |
| SCHEMBL8437201 | 0.78 | IL1RN (0.50) | ESR1ESR2CNR1CNR2TSHR | |
| SCHEMBL3055258 | 0.76 | TACR1 (0.50) | ESR1ESR2CNR1CNR2TSHR | |
| SCHEMBL3055256 | 0.76 | TACR1 (0.50) | ESR1ESR2CNR1CNR2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0451422-A1 | Pharmaceutically active fluoromethyltyrosine compounds | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-10-16 | — | — | EP | disclosed |