Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 5/20 | 0.55 |
| ▸ | CTRC | Q99895 | 1/20 | 0.51 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | PSD | A5PKW4 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9848052 | 0.89 | CYP19A1 (0.59) | CYP19A1CTRCNPC1RAB9ACYP3A4 | |
| SCHEMBL9705291 | 0.83 | CTRC (0.65) | CTRCNPC1RAB9AMAPTMEN1 | |
| SCHEMBL31191947 | 0.81 | CYP19A1 (0.67) | CYP19A1NPC1RAB9ACYP3A4MAPT | |
| SCHEMBL21841086 | 0.80 | CYP19A1 (0.61) | CYP19A1CYP11B1CYP11B2NPC1RAB9A | |
| SCHEMBL25458352 | 0.78 | CYP19A1 (0.51) | CYP19A1CTRCNPC1RAB9ACYP3A4 | |
| SCHEMBL30085876 | 0.78 | CYP19A1 (0.51) | CYP19A1CTRCNPC1RAB9ACYP3A4 | |
| SCHEMBL28803081 | 0.77 | CTRC (0.55) | CYP19A1CTRCMAPTMEN1KMT2A | |
| SCHEMBL29808904 | 0.77 | CTRC (0.55) | CYP19A1CTRCMAPTMEN1KMT2A | |
| SCHEMBL21689664 | 0.77 | CYP19A1 (0.57) | CYP19A1CTRCCYP11B1CYP11B2NPC1 | |
| SCHEMBL29620544 | 0.77 | CYP19A1 (0.57) | CYP19A1CTRCCYP11B1CYP11B2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0451585-A2 | 2-aryl-6-hetarylpyridine derivatives | BAYER AG (DE) | 1991-10-16 | — | — | EP | disclosed |