Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.45 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5931364 | 0.79 | MEN1 (1.00) | KMT2AMEN1MAPTHTTGAA | |
| SCHEMBL1162892 | 0.78 | MEN1 (0.62) | KMT2AMEN1MAPTHTTGAA | |
| SCHEMBL6139623 | 0.78 | MAPT (0.69) | KMT2AMEN1MAPTHTTGAA | |
| SCHEMBL2594017 | 0.78 | NAPRT (0.52) | KMT2AMEN1MAPTHTTGAA | |
| SCHEMBL28474124 | 0.78 | MEN1 (0.74) | KMT2AMEN1MAPTHPGDALOX15 | |
| SCHEMBL2594020 | 0.78 | NAPRT (0.52) | KMT2AMEN1MAPTHTTGAA | |
| SCHEMBL2594019 | 0.78 | NAPRT (0.52) | KMT2AMEN1MAPTHTTGAA | |
| SCHEMBL9564366 | 0.77 | GAA (0.50) | KMT2AMEN1MAPTHTTGAA | |
| SCHEMBL9564371 | 0.77 | GAA (0.50) | KMT2AMEN1MAPTHTTGAA | |
| SCHEMBL6218138 | 0.76 | MAPT (0.67) | KMT2AMEN1MAPTHTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0451585-A2 | 2-aryl-6-hetarylpyridine derivatives | BAYER AG (DE) | 1991-10-16 | — | — | EP | disclosed |