Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.74 |
| ▸ | MAPT | P10636 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5931364 | 0.85 | MEN1 (1.00) | MEN1KMT2AMAPTTP53ALDH1A1 | |
| SCHEMBL6139623 | 0.83 | MAPT (0.69) | MEN1KMT2AMAPTTP53ALDH1A1 | |
| SCHEMBL9210472 | 0.82 | MAPT (0.67) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL6139630 | 0.82 | MAPT (1.00) | MEN1KMT2AMAPTALDH1A1CA1 | |
| SCHEMBL6218138 | 0.82 | MAPT (0.67) | MEN1KMT2AMAPTTSHRALDH1A1 | |
| SCHEMBL16052890 | 0.81 | MEN1 (0.65) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL11048818 | 0.79 | MAPT (0.62) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL1162890 | 0.79 | MAPT (0.62) | MEN1KMT2AMAPTTSHRALDH1A1 | |
| SCHEMBL9848064 | 0.78 | KMT2A (0.66) | MEN1KMT2AMAPTTSHRTP53 | |
| SCHEMBL9619495 | 0.77 | MAPT (0.66) | MEN1KMT2AMAPTALDH1A1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111836801-B | Compounds for inhibiting TNIK and medical use thereof | 韩国化学硏究院 | 2024-02-02 | — | — | CN | disclosed |
| CN-111836801-A | Compound for inhibiting TNIK and medical application thereof | 韩国化学硏究院 | 2020-10-27 | — | — | CN | disclosed |