Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.76 |
| ▸ | RAB9A | P51151 | 9/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.76 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.76 |
| ▸ | TP53 | P04637 | 3/20 | 0.76 |
| ▸ | TSHR | P16473 | 3/20 | 0.76 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.76 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.76 |
| ▸ | RELA | Q04206 | 2/20 | 0.76 |
| ▸ | CASP3 | P42574 | 1/20 | 0.76 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.76 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.76 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.70 |
| ▸ | HPGD | P15428 | 5/20 | 0.70 |
| ▸ | CA1 | P00915 | 1/20 | 0.62 |
| ▸ | CA2 | P00918 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | GUSB | P08236 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12692353 | 0.86 | RAB9A (1.00) | NPC1RAB9AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL19649005 | 0.86 | RAB9A (0.81) | NPC1RAB9AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL12692468 | 0.83 | NPC1 (0.76) | NPC1RAB9AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL20193433 | 0.83 | RAB9A (0.69) | NPC1RAB9AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL12171339 | 0.81 | NPC1 (0.71) | NPC1RAB9AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL4879096 | 0.81 | NPC1 (0.73) | NPC1RAB9AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL5640017 | 0.81 | RAB9A (0.59) | NPC1RAB9AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL12692471 | 0.80 | NPC1 (0.66) | NPC1RAB9AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL6737766 | 0.80 | NPC1 (0.74) | NPC1RAB9AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL9737564 | 0.80 | RAB9A (0.58) | NPC1RAB9ATP53NFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0453846-A2 | Aryloxycarbonyl compounds | BAYER AG (DE) | 1991-10-30 | — | — | EP | disclosed |