Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 11/20 | 0.73 |
| ▸ | RAB9A | P51151 | 11/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.73 |
| ▸ | TP53 | P04637 | 4/20 | 0.73 |
| ▸ | TSHR | P16473 | 4/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.73 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.73 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.73 |
| ▸ | RELA | Q04206 | 2/20 | 0.73 |
| ▸ | CASP3 | P42574 | 1/20 | 0.73 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.73 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.73 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.72 |
| ▸ | HPGD | P15428 | 5/20 | 0.72 |
| ▸ | ATAD2 | Q6PL18 | 2/20 | 0.66 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | CA1 | P00915 | 1/20 | 0.60 |
| ▸ | CA2 | P00918 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19649005 | 0.87 | RAB9A (0.81) | NPC1RAB9AALDH1A1TP53TSHR | |
| SCHEMBL12692353 | 0.84 | RAB9A (1.00) | NPC1RAB9AALDH1A1TP53TSHR | |
| SCHEMBL1422987 | 0.82 | NPC1 (1.00) | NPC1RAB9AALDH1A1TP53TSHR | |
| SCHEMBL12692468 | 0.81 | NPC1 (0.76) | NPC1RAB9AALDH1A1TP53TSHR | |
| SCHEMBL9848071 | 0.81 | NPC1 (0.76) | NPC1RAB9AALDH1A1TP53TSHR | |
| SCHEMBL4882187 | 0.80 | NPC1 (0.74) | NPC1RAB9AALDH1A1TP53TSHR | |
| SCHEMBL16771408 | 0.79 | ATAD2 (1.00) | NPC1RAB9AALDH1A1TP53TSHR | |
| SCHEMBL18292319 | 0.79 | ATAD2 (0.66) | NPC1RAB9AALDH1A1TP53TSHR | |
| SCHEMBL714484 | 0.79 | NPC1 (1.00) | NPC1RAB9AALDH1A1TP53TSHR | |
| SCHEMBL4883712 | 0.79 | PKM (1.00) | NPC1RAB9AALDH1A1TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080015193-A1 | Certain azoles exhibiting ATP-utilizing enzyme inhibitory activity, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2008-01-17 | — | — | US | claimed |
| US-20080015193-A1 | Certain azoles exhibiting ATP-utilizing enzyme inhibitory activity, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2008-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080015193-A1 | Certain azoles exhibiting ATP-utilizing enzyme inhibitory activity, compositions, and uses thereof | ATP5ME, ATP5MG, ATP5MK | NPC1 2981/4885RAB9A 3960/4885ALDH1A1 404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.