Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.48 |
| ▸ | FYN | P06241 | 1/20 | 0.48 |
| ▸ | DAO | P14920 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 3/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.34 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9564413 | 0.78 | CES2 (0.40) | MEN1KMT2AMAPTCES2CES1 | |
| SCHEMBL9564422 | 0.78 | CES2 (0.40) | MEN1KMT2AMAPTCES2CES1 | |
| SCHEMBL10810400 | 0.78 | CES2 (0.50) | CES2CES1LCKFYNDAO | |
| SCHEMBL10810404 | 0.78 | CES2 (0.50) | CES2CES1LCKFYNDAO | |
| SCHEMBL3309279 | 0.76 | LCK (0.55) | MEN1KMT2AMAPTCES2CES1 | |
| SCHEMBL3309282 | 0.76 | LCK (0.55) | MEN1KMT2AMAPTCES2CES1 | |
| SCHEMBL3309285 | 0.76 | LCK (0.55) | MEN1KMT2AMAPTCES2CES1 | |
| SCHEMBL3310255 | 0.73 | LCK (0.47) | MAPTCES2CES1LCKFYN | |
| SCHEMBL3310260 | 0.73 | LCK (0.47) | MAPTCES2CES1LCKFYN | |
| SCHEMBL6050171 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0451585-A2 | 2-aryl-6-hetarylpyridine derivatives | BAYER AG (DE) | 1991-10-16 | — | — | EP | disclosed |