Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 2/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9564413 | 1.00 | CES2 (0.40) | CES2CES1HDAC1LCKFYN | |
| SCHEMBL9848078 | 0.78 | MEN1 (0.56) | CES2CES1HDAC1LCKFYN | |
| SCHEMBL9564371 | 0.77 | GAA (0.50) | HDAC1HPGDMEN1KMT2ACA1 | |
| SCHEMBL9564366 | 0.77 | GAA (0.50) | HDAC1HPGDMEN1KMT2ACA1 | |
| SCHEMBL10874394 | 0.77 | MAPT (0.48) | HPGDNPC1RAB9AMEN1KMT2A | |
| SCHEMBL9564386 | 0.75 | DAO (0.41) | DAOHPGDRAB9AMEN1KMT2A | |
| SCHEMBL9564370 | 0.74 | GAA (0.48) | HDAC1HPGDNPC1RAB9AMEN1 | |
| SCHEMBL9564376 | 0.74 | GAA (0.48) | HDAC1HPGDNPC1RAB9AMEN1 | |
| SCHEMBL10869367 | 0.73 | NR4A1 (0.43) | CES2CES1MEN1KMT2AMAPT | |
| SCHEMBL7223253 | 0.73 | HDAC1 (0.60) | CES2CES1HDAC1LCKFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563686-A1 | Utilization of 3 substituted amino isoxazole derivatives against endoparasites, new 3 substituted amino isoxazols and process for their preparation | BAYER AG (DE) | 1993-10-06 | — | — | EP | disclosed |