Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 4/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9597108 | 1.00 | KDM4E (0.46) | KDM4ELMNAESR1CHRM1SLC6A4 | |
| SCHEMBL9597495 | 0.84 | KDM4E (0.51) | KDM4ELMNAESR1CHRM1SLC6A4 | |
| SCHEMBL9600259 | 0.83 | KDM4E (0.47) | KDM4ELMNAESR1CHRM1SLC6A4 | |
| SCHEMBL9596929 | 0.82 | ESR1 (0.50) | KDM4ELMNAESR1CHRM1SLC6A4 | |
| SCHEMBL9596477 | 0.79 | KDM4E (0.48) | KDM4ELMNAESR1CHRM1SLC6A4 | |
| SCHEMBL9596707 | 0.78 | KDM4E (0.45) | KDM4ELMNAESR1CHRM1SLC6A4 | |
| SCHEMBL9596535 | 0.76 | KDM4E (0.52) | KDM4ELMNAESR1CHRM1SLC6A4 | |
| SCHEMBL21046146 | 0.76 | LMNA (0.59) | KDM4ELMNAESR1CHRM1SLC6A4 | |
| SCHEMBL21046155 | 0.76 | LMNA (0.59) | KDM4ELMNAESR1CHRM1SLC6A4 | |
| SCHEMBL21046147 | 0.76 | LMNA (0.59) | KDM4ELMNAESR1CHRM1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0430037-A2 | Process for producing 2-carbon-substituted carbapenem derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-06-05 | — | — | EP | disclosed |