Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 5/20 | 0.54 |
| ▸ | WNT3A | P56704 | 4/20 | 0.54 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9202965 | 0.83 | KEAP1 (0.50) | ALDH1A1GAAMAPTTDP1LMNA | |
| SCHEMBL30121738 | 0.77 | NR4A2 (0.85) | CTNNB1WNT3ANR4A2ALDH1A1CYP2C19 | |
| SCHEMBL719034 | 0.77 | NR4A2 (0.85) | CTNNB1WNT3ANR4A2ALDH1A1CYP2C19 | |
| SCHEMBL9195700 | 0.74 | ALDH1A1 (0.77) | CTNNB1WNT3ANR4A2ALDH1A1CYP2C19 | |
| SCHEMBL15979683 | 0.71 | CTNNB1 (0.59) | CTNNB1WNT3ANR4A2ALDH1A1CYP2C19 | |
| SCHEMBL18755271 | 0.71 | NR4A2 (0.68) | CTNNB1WNT3ANR4A2ALDH1A1CYP2C19 | |
| SCHEMBL112293 | 0.71 | — | — | |
| SCHEMBL354105 | 0.71 | NR4A2 (1.00) | CTNNB1WNT3ANR4A2ALDH1A1CYP2C19 | |
| SCHEMBL27945874 | 0.71 | ALDH1A1 (0.87) | CTNNB1WNT3ANR4A2ALDH1A1CYP2C19 | |
| SCHEMBL15969192 | 0.71 | CTNNB1 (1.00) | CTNNB1WNT3ANR4A2ALDH1A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1040105-C | Aminoketone derivatives and use thereof | MITZUI TOATSU CHEMICALS INC (JP) | 1998-10-07 | — | — | CN | disclosed |
| EP-0414391-A2 | Aminoketone derivatives and use thereof | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-02-27 | — | — | EP | disclosed |