Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MERTK | Q12866 | 1/20 | 0.36 |
| ▸ | GHSR | Q92847 | 5/20 | 0.35 |
| ▸ | HTR6 | P50406 | 4/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | KHK | P50053 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9848157 | 0.99 | POLB (0.38) | POLBMERTKGHSRHTR6CHRNB4 | |
| SCHEMBL9848173 | 0.92 | POLB (0.37) | POLBMERTKGHSRHTR6CHRNB4 | |
| SCHEMBL27318418 | 0.74 | TRPV4 (0.42) | NPC1HTTRAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9848159 | 0.73 | TRPV4 (0.43) | NPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL9848134 | 0.70 | S1PR1 (0.41) | POLBMERTKHTR6HTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9848111 | 0.67 | POLB (0.41) | POLBKHK | |
| SCHEMBL9848156 | 0.66 | CHRNB2 (0.33) | POLB | |
| Benzamide SCHEMBL3289076 | 0.66 | POLB (0.47) | POLBGHSRHTR6CHRNB4CHRNA3 | |
| SCHEMBL9848174 | 0.65 | TACR3 (0.42) | NPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9848200 | 0.65 | POLB (0.46) | POLBGHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0414391-A2 | Aminoketone derivatives and use thereof | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-02-27 | — | — | EP | disclosed |