Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | ULK1 | O75385 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4129794 | 0.81 | EPHX2 (0.69) | RAB9APKMEPHX2HTT | |
| SCHEMBL27265696 | 0.81 | EPHX2 (0.69) | RAB9APKMEPHX2HTT | |
| SCHEMBL9848520 | 0.76 | — | — | |
| SCHEMBL9848401 | 0.76 | — | — | |
| SCHEMBL9848414 | 0.76 | — | — | |
| SCHEMBL9848453 | 0.76 | — | — | |
| SCHEMBL9848454 | 0.74 | — | — | |
| SCHEMBL11432520 | 0.73 | PKM (0.62) | RAB9APKMEPHX2NPC1HTT | |
| SCHEMBL8777922 | 0.72 | EPHX2 (0.66) | RAB9AEPHX2HTT | |
| SCHEMBL4127306 | 0.71 | EPHX2 (0.68) | RAB9AEPHX2NPC1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0432442-A1 | ACAT inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-06-19 | — | — | EP | claimed |