Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10589370 | 0.80 | MEN1 (0.63) | SOAT1KMT2A | |
| SCHEMBL10065403 | 0.77 | P2RX7 (0.49) | — | |
| SCHEMBL13480578 | 0.73 | SMN1; SMN2 (0.58) | SMN1; SMN2 | |
| SCHEMBL26728285 | 0.73 | P2RX7 (0.51) | — | |
| SCHEMBL9295699 | 0.73 | NPC1 (0.55) | SMN1; SMN2LPAR1 | |
| SCHEMBL462304 | 0.72 | LPAR1 (0.66) | LMNAKMT2ASMN1; SMN2LPAR1 | |
| SCHEMBL6925202 | 0.72 | P2RX7 (0.49) | — | |
| SCHEMBL9723446 | 0.71 | SOAT1 (0.53) | SOAT1LMNAKMT2A | |
| SCHEMBL31036963 | 0.71 | P2RX7 (0.55) | — | |
| SCHEMBL8321568 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0432442-A1 | ACAT inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-06-19 | — | — | EP | disclosed |