SCHEMBL9723446

SCHEMBL9723446

CC(C)c1cccc(C(C)C)c1NC(=O)NC(=O)NCc1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SOAT1 P35610 2/20 0.53
SOAT2 O75908 1/20 0.53
LMNA P02545 1/20 0.52
KMT2A Q03164 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9723517 0.83 KMT2A (0.61) LMNAKMT2A
SCHEMBL9843929 0.82 SOAT1 (0.65) SOAT1SOAT2LMNAKMT2A
SCHEMBL9680183 0.80 ANPEP (0.63) SOAT1SOAT2
SCHEMBL9513684 0.79 EPHX1 (0.63) SOAT1SOAT2KMT2A
SCHEMBL9723461 0.79 SOAT2 (0.46) SOAT1SOAT2LMNAKMT2A
SCHEMBL9723538 0.79 KMT2A (0.60) LMNAKMT2A
SCHEMBL9723419 0.78 SOAT2 (0.51) SOAT1SOAT2LMNAKMT2A
SCHEMBL6033584 0.78 TP53 (0.75) LMNAKMT2A
SCHEMBL9848470 0.77
SCHEMBL9848403 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5153223-A Anticholesterol agents WARNER-LAMBERT COMPANY (US) 1992-10-06 US claimed