Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 10/20 | 0.62 |
| ▸ | CTSK | P43235 | 9/20 | 0.62 |
| ▸ | CTSB | P07858 | 4/20 | 0.62 |
| ▸ | CTSL | P07711 | 2/20 | 0.62 |
| ▸ | REN | P00797 | 4/20 | 0.53 |
| ▸ | CTSD | P07339 | 1/20 | 0.53 |
| ▸ | AKT1 | P31749 | 1/20 | 0.53 |
| ▸ | ACE | P12821 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5050550 | 0.83 | CTSS (0.69) | CTSSCTSKCTSBCTSLREN | |
| SCHEMBL7295862 | 0.83 | CTSS (0.69) | CTSSCTSKCTSBCTSLREN | |
| SCHEMBL7295855 | 0.83 | CTSS (0.69) | CTSSCTSKCTSBCTSLREN | |
| SCHEMBL16999951 | 0.82 | CTSS (0.71) | CTSSCTSKCTSBCTSLREN | |
| SCHEMBL9637243 | 0.82 | ACE (0.53) | CTSDACE | |
| SCHEMBL9637249 | 0.82 | ACE (0.53) | CTSDACE | |
| SCHEMBL3498556 | 0.81 | CTSS (0.64) | CTSSCTSKCTSBCTSLREN | |
| SCHEMBL22962299 | 0.81 | CTSS (0.70) | CTSSCTSKCTSBCTSLREN | |
| SCHEMBL10135746 | 0.81 | CTSS (0.70) | CTSSCTSKCTSBCTSLREN | |
| SCHEMBL15468056 | 0.81 | CTSS (0.70) | CTSSCTSKCTSBCTSLREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0428849-A2 | Retroviral protease inhibitors | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-05-29 | — | — | EP | disclosed |