Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 10/20 | 0.53 |
| ▸ | MME | P08473 | 6/20 | 0.53 |
| ▸ | CPA1 | P15085 | 6/20 | 0.53 |
| ▸ | ACE2 | Q9BYF1 | 6/20 | 0.53 |
| ▸ | CTRB1 | P17538 | 3/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | CTSC | P53634 | 1/20 | 0.44 |
| ▸ | CTSD | P07339 | 1/20 | 0.44 |
| ▸ | GNPAT | O15228 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9637243 | 1.00 | ACE (0.53) | ACEMMECPA1ACE2CTRB1 | |
| SCHEMBL7259322 | 0.94 | CTSD (0.49) | ACEMMECPA1ACE2CTRB1 | |
| SCHEMBL2184328 | 0.87 | MME (0.47) | ACEMMECPA1ACE2HDAC3 | |
| SCHEMBL9637180 | 0.85 | CTSC (0.54) | ACEMMECPA1ACE2CTRB1 | |
| SCHEMBL9637178 | 0.85 | CTSC (0.54) | ACEMMECPA1ACE2CTRB1 | |
| SCHEMBL29876711 | 0.83 | ACE (0.58) | ACEMMECPA1ACE2CTRB1 | |
| SCHEMBL9848482 | 0.82 | CTSS (0.62) | ACECTSD | |
| SCHEMBL9637159 | 0.82 | MMP2 (0.47) | ACEMMECPA1ACE2 | |
| SCHEMBL9636716 | 0.82 | MMP2 (0.47) | ACEMMECPA1ACE2 | |
| SCHEMBL9636709 | 0.82 | MMP2 (0.47) | ACEMMECPA1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268678-B1 | NOVEL 5-FLUOROURIDINE COMPOUNDS AND PROCESS FOR THEIR PREPARATION | FUJI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1992-07-29 | — | — | EP | claimed |
| US-4892939-A | ANTITUMOR, ANTIVIRAL AND IMMUNOSUPRESSIVE AGENTS | FUJI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1990-01-09 | — | — | US | claimed |