Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 7/20 | 0.47 |
| ▸ | PPARG | P37231 | 6/20 | 0.47 |
| ▸ | CTRC | Q99895 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7158307 | 0.90 | CTRC (0.47) | PPARAPPARGCTRCALOX5CNR2 | |
| SCHEMBL19127531 | 0.90 | CTRC (0.47) | PPARAPPARGCTRCALOX5CNR2 | |
| SCHEMBL664608 | 0.84 | CTRC (0.46) | PPARAPPARGCTRCALOX5CNR2 | |
| SCHEMBL4748765 | 0.84 | CTRC (0.46) | PPARAPPARGCTRCALOX5CNR2 | |
| SCHEMBL23566860 | 0.82 | CTRC (0.51) | PPARAPPARGCTRCALOX5CNR2 | |
| SCHEMBL18259710 | 0.82 | CTRC (0.51) | PPARAPPARGCTRCALOX5CNR2 | |
| SCHEMBL28558780 | 0.81 | CTRC (0.47) | PPARAPPARGCTRCALOX5CNR2 | |
| SCHEMBL4748733 | 0.79 | PPARG (0.49) | PPARAPPARGCTRCALOX5CNR2 | |
| SCHEMBL666291 | 0.79 | PPARG (0.49) | PPARAPPARGCTRCALOX5CNR2 | |
| SCHEMBL5574790 | 0.78 | PPARG (0.51) | PPARAPPARGALOX5ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0408506-A2 | New triazole compounds | CIBA-GEIGY AG (CH) | 1991-01-16 | — | — | EP | disclosed |