Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 11/20 | 0.51 |
| ▸ | PPARA | Q07869 | 11/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23566860 | 0.88 | CTRC (0.51) | PPARGPPARACYP1A2GAACYP2C9 | |
| SCHEMBL18259710 | 0.88 | CTRC (0.51) | PPARGPPARACYP1A2GAACYP2C9 | |
| SCHEMBL5696315 | 0.86 | ALDH1A1 (0.44) | PPARGPPARACYP1A2GAACYP2C9 | |
| SCHEMBL9848547 | 0.78 | PPARA (0.47) | PPARGPPARACYP1A2GAACYP2C9 | |
| SCHEMBL28057203 | 0.78 | PPARA (0.47) | PPARGPPARACYP1A2GAACYP2C9 | |
| SCHEMBL17904962 | 0.78 | PPARG (0.62) | PPARGPPARACYP1A2GAACYP2C9 | |
| SCHEMBL8846721 | 0.78 | PPARG (0.62) | PPARGPPARACYP1A2GAACYP2C9 | |
| SCHEMBL8935857 | 0.78 | PPARG (0.62) | PPARGPPARACYP1A2GAACYP2C9 | |
| SCHEMBL11322441 | 0.78 | CYP1A2 (0.53) | PPARGPPARACYP1A2GAACYP2C9 | |
| SCHEMBL1933913 | 0.78 | CYP1A2 (0.53) | PPARGPPARACYP1A2GAACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778702-A2 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006020276-A2 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2006-02-23 | — | — | WO | disclosed |