Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | GRM7 | Q14831 | 3/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.39 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9848561 | 0.90 | GRM7 (0.40) | GRM7GRM4GRM1 | |
| SCHEMBL9848554 | 0.79 | GRM7 (0.37) | GRM7GRM4GRM1 | |
| SCHEMBL9848591 | 0.78 | GRM7 (0.42) | GRM7GRM4GRM1 | |
| SCHEMBL8349482 | 0.69 | HTR2C (0.53) | HTR2AHTR2C | |
| SCHEMBL10338402 | 0.68 | CHRM1 (0.42) | GRM7GRM4 | |
| SCHEMBL21872466 | 0.68 | HTR2C (0.54) | HTR2AHTR2C | |
| SCHEMBL9848585 | 0.67 | GPR84 (0.47) | GRM7GRM4GRM1 | |
| SCHEMBL10615889 | 0.66 | PARK7 (0.50) | GRM7GRM4GRM1 | |
| SCHEMBL11721047 | 0.66 | GRM7 (0.43) | GRM7GRM4GRM1 | |
| SCHEMBL9823500 | 0.65 | GRM7 (0.46) | GRM7GRM4GRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409025-A2 | N-[Indol-6-yl]-heterocyclic compounds | BAYER AG (DE) | 1991-01-23 | — | — | EP | claimed |
| EP-0409025-A2 | N-[Indol-6-yl]-heterocyclic compounds | BAYER AG (DE) | 1991-01-23 | — | — | EP | disclosed |