Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 13/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.52 |
| ▸ | BACE2 | Q9Y5Z0 | 4/20 | 0.51 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.51 |
| ▸ | MME | P08473 | 1/20 | 0.48 |
| ▸ | CTSD | P07339 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9848690 | 0.91 | OPRD1 (0.62) | BACE1OPRD1BACE2CTSD | |
| SCHEMBL9848664 | 0.91 | OPRD1 (0.61) | BACE1OPRD1BACE2CTSD | |
| SCHEMBL9848681 | 0.90 | BACE1 (0.53) | BACE1OPRD1BACE2FOLH1CTSD | |
| SCHEMBL9848649 | 0.87 | BACE1 (0.55) | BACE1BACE2MMECTSD | |
| SCHEMBL9848616 | 0.87 | BACE1 (0.57) | BACE1BACE2CTSD | |
| SCHEMBL9848695 | 0.86 | BACE1 (0.50) | BACE1OPRD1BACE2FOLH1CTSD | |
| SCHEMBL9848623 | 0.85 | OPRD1 (0.47) | BACE1OPRD1BACE2FOLH1CTSD | |
| SCHEMBL9848624 | 0.84 | OPRD1 (0.51) | BACE1OPRD1BACE2CTSD | |
| SCHEMBL9848648 | 0.84 | BACE1 (0.48) | BACE1OPRD1BACE2FOLH1CTSD | |
| SCHEMBL30419543 | 0.84 | BACE1 (0.57) | BACE1OPRD1BACE2FOLH1CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0438873-A1 | Inhibitor of ribonucleotide reductase of herpes viruses | MERCK & CO. INC. (US) | 1991-07-31 | — | — | EP | disclosed |