Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 19/20 | 0.52 |
| ▸ | CTSD | P07339 | 4/20 | 0.52 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30099570 | 0.89 | BACE1 (0.54) | BACE1CTSDBACE2 | |
| SCHEMBL31181176 | 0.89 | MME (0.50) | BACE1 | |
| SCHEMBL29558228 | 0.89 | BACE1 (0.54) | BACE1CTSDBACE2 | |
| SCHEMBL30011640 | 0.87 | ALDH1A1 (0.47) | BACE1CTSDBACE2 | |
| SCHEMBL29366355 | 0.87 | ALDH1A1 (0.47) | BACE1CTSDBACE2 | |
| SCHEMBL30052089 | 0.87 | ALDH1A1 (0.50) | — | |
| SCHEMBL29798028 | 0.86 | BACE1 (0.57) | BACE1CTSDBACE2 | |
| SCHEMBL29630899 | 0.86 | ECE1 (0.56) | BACE1CTSD | |
| SCHEMBL29973181 | 0.85 | BACE1 (0.48) | BACE1CTSD | |
| SCHEMBL30737533 | 0.85 | ECE1 (0.47) | BACE1CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0438873-A1 | Inhibitor of ribonucleotide reductase of herpes viruses | MERCK & CO. INC. (US) | 1991-07-31 | — | — | EP | disclosed |