Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 7/20 | 0.48 |
| ▸ | CTSD | P07339 | 4/20 | 0.48 |
| ▸ | ECE1 | P42892 | 2/20 | 0.48 |
| ▸ | ENPEP | Q07075 | 5/20 | 0.46 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29630874 | 0.94 | ECE1 (0.54) | BACE1CTSDECE1ENPEPPDCD1LG2 | |
| SCHEMBL29630884 | 0.94 | ECE1 (0.54) | BACE1CTSDECE1ENPEPPDCD1LG2 | |
| SCHEMBL29630710 | 0.94 | ECE1 (0.54) | BACE1CTSDECE1ENPEPPDCD1LG2 | |
| SCHEMBL29630775 | 0.94 | ECE1 (0.54) | BACE1CTSDECE1ENPEPPDCD1LG2 | |
| SCHEMBL30123289 | 0.92 | ENPEP (0.48) | ENPEP | |
| SCHEMBL29870994 | 0.92 | ECE1 (0.51) | BACE1ECE1ENPEPPDCD1LG2CD274 | |
| SCHEMBL14571182 | 0.89 | BACE1 (0.50) | BACE1CTSDECE1 | |
| SCHEMBL29697180 | 0.88 | PDCD1LG2 (0.50) | BACE1CTSDECE1PDCD1LG2CD274 | |
| SCHEMBL29375430 | 0.88 | MME (0.46) | BACE1ENPEP | |
| SCHEMBL31571456 | 0.87 | ECE1 (0.47) | BACE1CTSDECE1ENPEPPDCD1LG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4067370-A1 | HIGH PENETRATION PRODRUG COMPOSITIONS OF PEPTIDES AND PEPTIDE RELATED COMPOUNDS | Yu, Chongxi (US) | 2022-10-05 | — | — | EP | disclosed |