Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 4/20 | 0.61 |
| ▸ | BACE1 | P56817 | 12/20 | 0.52 |
| ▸ | BACE2 | Q9Y5Z0 | 3/20 | 0.50 |
| ▸ | CTSD | P07339 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9848671 | 0.90 | OPRD1 (0.59) | OPRD1BACE1BACE2CTSD | |
| SCHEMBL9848704 | 0.90 | OPRD1 (0.60) | OPRD1BACE1BACE2CTSDCASP1 | |
| SCHEMBL9848690 | 0.90 | OPRD1 (0.62) | OPRD1BACE1BACE2CTSD | |
| SCHEMBL9848664 | 0.89 | OPRD1 (0.61) | OPRD1BACE1BACE2CTSD | |
| SCHEMBL9848670 | 0.89 | OPRD1 (0.61) | OPRD1BACE1BACE2CTSDCASP1 | |
| SCHEMBL9848656 | 0.87 | OPRD1 (0.62) | OPRD1BACE1BACE2CTSDCASP1 | |
| SCHEMBL30408002 | 0.87 | OPRD1 (0.61) | OPRD1BACE1BACE2CTSDCASP1 | |
| SCHEMBL30407854 | 0.86 | OPRD1 (0.57) | OPRD1BACE1BACE2CTSD | |
| SCHEMBL31062503 | 0.85 | OPRD1 (0.61) | OPRD1BACE1BACE2CTSD | |
| SCHEMBL30373869 | 0.85 | OPRD1 (0.61) | OPRD1BACE1BACE2CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0438873-A1 | Inhibitor of ribonucleotide reductase of herpes viruses | MERCK & CO. INC. (US) | 1991-07-31 | — | — | EP | disclosed |