Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 4/20 | 0.61 |
| ▸ | BACE1 | P56817 | 3/20 | 0.50 |
| ▸ | GRB2 | P62993 | 1/20 | 0.49 |
| ▸ | KISS1R | Q969F8 | 2/20 | 0.48 |
| ▸ | CTSD | P07339 | 2/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9848682 | 0.89 | OPRD1 (0.61) | OPRD1BACE1CTSDCASP1BACE2 | |
| SCHEMBL30408002 | 0.89 | OPRD1 (0.61) | OPRD1BACE1KISS1RCTSDCASP1 | |
| SCHEMBL30974364 | 0.88 | CTSD (0.54) | OPRD1CTSD | |
| SCHEMBL9848690 | 0.88 | OPRD1 (0.62) | OPRD1BACE1CTSDBACE2 | |
| SCHEMBL31062518 | 0.87 | OPRD1 (0.61) | OPRD1BACE1CASP1BACE2 | |
| SCHEMBL9848664 | 0.87 | OPRD1 (0.61) | OPRD1BACE1CTSDBACE2 | |
| SCHEMBL9848704 | 0.86 | OPRD1 (0.60) | OPRD1BACE1CTSDCASP1BACE2 | |
| SCHEMBL30844076 | 0.86 | ACE (0.54) | OPRD1BACE1GRB2KISS1R | |
| SCHEMBL9848656 | 0.85 | OPRD1 (0.62) | OPRD1BACE1CTSDCASP1BACE2 | |
| SCHEMBL30638818 | 0.85 | ACE (0.55) | OPRD1GRB2KISS1RCTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0438873-A1 | Inhibitor of ribonucleotide reductase of herpes viruses | MERCK & CO. INC. (US) | 1991-07-31 | — | — | EP | disclosed |