Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.42 |
| ▸ | BCAT2 | O15382 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | DAO | P14920 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL30209252 | 0.91 | GPR35 (0.36) | GPR35BCAT2ALDH1A1DAOKDM4E | |
| SCHEMBL25401807 | 0.83 | CSNK2A2 (0.50) | ALDH1A1KDM4EKMT2AMAPTPKM | |
| SCHEMBL30209314 | 0.76 | KDM4E (0.51) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL1697942 | 0.74 | HCAR2 (0.37) | GPR35ALDH1A1DAOKDM4EMEN1 | |
| SCHEMBL5036393 | 0.72 | — | — | |
| SCHEMBL29748815 | 0.70 | DAO (0.39) | GPR35BCAT2ALDH1A1DAOKDM4E | |
| SCHEMBL10769399 | 0.70 | GPR35 (0.38) | GPR35ALDH1A1DAOKDM4EMEN1 | |
| SCHEMBL30421721 | 0.70 | GPR35 (0.40) | GPR35ALDH1A1DAOKDM4EMEN1 | |
| SCHEMBL29924439 | 0.70 | GPR35 (0.50) | GPR35ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL5039279 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250002471-A1 | 6-SUBSTITUTED INDOLE COMPOUNDS | GILEAD SCIENCES, INC. | 2025-01-02 | — | — | US | disclosed |
| CN-118974037-A | Benzobicyclo compound and preparation method and application thereof | 广州市联瑞制药有限公司 | 2024-11-15 | — | — | CN | disclosed |
| CN-115667238-B | Five-membered ring derivative and application thereof in medicine | 西藏海思科制药有限公司 | 2024-08-23 | — | — | CN | disclosed |
| US-20240124470-A1 | FIVE-MEMBERED RING DERIVATIVE AND MEDICAL USE THEREOF | XIZANG HAISCO PHARMACEUTICAL CO., LTD. (CN) | 2024-04-18 | — | — | US | disclosed |
| WO-2024041609-A1 | BENZO BICYCLIC COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF | 广州市联瑞制药有限公司 | 2024-02-29 | — | — | WO | disclosed |
| CN-117177970-A | Polycyclic derivative regulator, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-12-05 | — | — | CN | disclosed |
| EP-4269399-A1 | FIVE-MEMBERED RING DERIVATIVE AND MEDICAL USE THEREOF | Sichuan Haisco Pharmaceutical Co., Ltd. (CN) | 2023-11-01 | — | — | EP | disclosed |
| EP-4267560-A1 | 6-SUBSTITUTED INDOLE COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2023-11-01 | — | — | EP | disclosed |
| WO-2023130878-A1 | GLP-1 AGONIST SALT, AND CRYSTAL FORM AND MEDICAL USE THEREOF | 海思科医药集团股份有限公司 | 2023-07-13 | — | — | WO | disclosed |
| CN-113831337-B | GLP-1 receptor agonist, and pharmaceutical composition and use thereof | 广州市恒诺康医药科技有限公司 | 2023-03-24 | — | — | CN | disclosed |
| CN-115667238-A | Five-membered ring derivative and application thereof in medicine | 四川海思科制药有限公司 | 2023-01-31 | — | — | CN | disclosed |
| WO-2022228490-A1 | POLYCYCLIC DERIVATIVE MODULATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2022-11-03 | — | — | WO | disclosed |
| WO-2022140325-A1 | 6-SUBSTITUTED INDOLE COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2022-06-30 | — | — | WO | disclosed |
| WO-2022140325-A1 | 6-SUBSTITUTED INDOLE COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2022-06-30 | — | — | WO | disclosed |
| WO-2022135572-A1 | FIVE-MEMBERED RING DERIVATIVE AND MEDICAL USE THEREOF | 四川海思科制药有限公司 | 2022-06-30 | — | — | WO | disclosed |
| EP-0407102-A1 | Substituted imidazo-fused 5-membered ring heterocycles as angiotensin II antagonists | MERCK & CO. INC. (US) | 1991-01-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240124470-A1 | FIVE-MEMBERED RING DERIVATIVE AND MEDICAL USE THEREOF | SLC5A1, SLC5A2, CYP11B2 | GPR35 414/4885BCAT2 486/4885ALDH1A1 1470/4885 |
| US-20250002471-A1 | 6-SUBSTITUTED INDOLE COMPOUNDS | SSB, IDO1, IDO2 | GPR35 1158/4885BCAT2 2360/4885ALDH1A1 2479/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.