Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.52 |
| ▸ | RXRA | P19793 | 4/20 | 0.43 |
| ▸ | RXRB | P28702 | 4/20 | 0.43 |
| ▸ | RXRG | P48443 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9440740 | 0.94 | SIRT2 (0.47) | SIRT2RXRARXRBRXRGNPSR1 | |
| SCHEMBL9848741 | 0.84 | SIRT2 (0.54) | SIRT2RXRARXRBRXRGNPSR1 | |
| SCHEMBL1363162 | 0.78 | SIRT2 (0.49) | SIRT2RXRARXRBRXRGNPSR1 | |
| SCHEMBL10833341 | 0.75 | RXRA (0.37) | SIRT2RXRARXRBRXRGALDH1A1 | |
| SCHEMBL9440752 | 0.74 | RXRA (0.33) | SIRT2RXRARXRBRXRGNPSR1 | |
| SCHEMBL10834256 | 0.74 | RXRA (0.58) | RXRARXRBRXRGALDH1A1HTT | |
| SCHEMBL5212038 | 0.73 | RXRA (0.60) | RXRARXRBRXRGALDH1A1CACNA1G | |
| SCHEMBL5207120 | 0.72 | NR4A2 (0.48) | RXRARXRBRXRGCACNA1GMEN1 | |
| SCHEMBL963990 | 0.71 | SIRT2 (0.40) | SIRT2RXRARXRBRXRGNPSR1 | |
| SCHEMBL5206850 | 0.70 | RXRA (0.46) | RXRARXRBRXRGALDH1A1CACNA1G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0440183-A1 | Oxazole compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-08-07 | — | — | EP | claimed |