Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 3/20 | 0.33 |
| ▸ | RXRB | P28702 | 3/20 | 0.33 |
| ▸ | RXRG | P48443 | 3/20 | 0.33 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.30 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9440740 | 0.81 | SIRT2 (0.47) | RXRARXRBRXRGCACNA1GALDH1A1 | |
| SCHEMBL9848736 | 0.74 | SIRT2 (0.52) | RXRARXRBRXRGCACNA1GALDH1A1 | |
| SCHEMBL9848741 | 0.73 | SIRT2 (0.54) | RXRARXRBRXRGALDH1A1NPSR1 | |
| SCHEMBL10832467 | 0.71 | TARBP2 (0.41) | RXRARXRBRXRGALDH1A1TARBP2 | |
| SCHEMBL10833341 | 0.62 | RXRA (0.37) | RXRARXRBRXRGCACNA1GALDH1A1 | |
| SCHEMBL10834256 | 0.62 | RXRA (0.58) | RXRARXRBRXRGALDH1A1 | |
| SCHEMBL9441135 | 0.62 | RAB9A (0.52) | ALDH1A1TARBP2 | |
| SCHEMBL5212038 | 0.61 | RXRA (0.60) | RXRARXRBRXRGCACNA1GALDH1A1 | |
| SCHEMBL15578243 | 0.61 | SMN1; SMN2 (0.41) | RXRARXRBRXRGALDH1A1 | |
| SCHEMBL9440768 | 0.61 | SIRT2 (0.38) | RXRARXRBRXRGALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5371098-A | Use of oxazole compounds to treat osteoporosis | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-12-06 | — | — | US | claimed |