Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7328569 | 0.92 | TSHR (0.46) | HDAC11LMNASLC22A6TBXA2RHSD17B10 | |
| SCHEMBL10823022 | 0.80 | IMPDH2 (0.49) | IMPDH2IMPDH1 | |
| SCHEMBL28029522 | 0.73 | AKR1B1 (0.42) | HDAC11SLC22A6HSD17B10TSHRAKR1B1 | |
| SCHEMBL29311921 | 0.73 | HPGD (0.45) | MAPK1HSD17B10ALDH1A1FFAR1 | |
| SCHEMBL29311924 | 0.71 | TYR (0.46) | MAPK1SLC6A3LMNAHSD17B10ALDH1A1 | |
| SCHEMBL9235513 | 0.70 | FASN (0.35) | MAPK1ALDH1A1 | |
| SCHEMBL14030867 | 0.70 | TYR (0.48) | SLC6A3LMNAHSD17B10ALDH1A1ESR1 | |
| SCHEMBL29311970 | 0.70 | NOS2 (0.32) | — | |
| SCHEMBL12134619 | 0.70 | TYR (0.48) | SLC6A3LMNAHSD17B10ALDH1A1ESR1 | |
| SCHEMBL29311917 | 0.70 | TYR (0.48) | SLC6A3LMNAHSD17B10ALDH1A1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0446809-A1 | New process for the synthesis of 5-acyloxy and 5-alkoxy-2,3-dihydro-4,6,7-trimethyl-2-(RS)-benzofuranacetic acids | BIOMEDICA FOSCAMA INDUSTRIA CHIMICO-FARMACEUTICA S.P.A. (IT) | 1991-09-18 | — | — | EP | claimed |
| EP-0446809-A1 | New process for the synthesis of 5-acyloxy and 5-alkoxy-2,3-dihydro-4,6,7-trimethyl-2-(RS)-benzofuranacetic acids | BIOMEDICA FOSCAMA INDUSTRIA CHIMICO-FARMACEUTICA S.P.A. (IT) | 1991-09-18 | — | — | EP | disclosed |