Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.54 |
| ▸ | CES1 | P23141 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14523011 | 0.94 | THRB (0.48) | THRBCES1TSHRALDH1A1HIF1A | |
| SCHEMBL11484128 | 0.82 | CES1 (0.57) | CES1ALDH1A1HIF1ACYP3A4TDP1 | |
| SCHEMBL17320925 | 0.82 | THRB (0.59) | THRBTSHRALDH1A1HIF1ATP53 | |
| SCHEMBL9848763 | 0.81 | CES1 (0.51) | THRBCES1TSHRALDH1A1HIF1A | |
| SCHEMBL10437472 | 0.79 | THRB (0.56) | THRBTSHRALDH1A1HIF1ATP53 | |
| SCHEMBL28881924 | 0.79 | CES1 (0.57) | THRBCES1TSHRALDH1A1TP53 | |
| SCHEMBL274928 | 0.79 | CES1 (0.56) | CES1TSHRALDH1A1HIF1AHSD17B10 | |
| SCHEMBL7591391 | 0.79 | CES1 (0.56) | CES1TSHRALDH1A1HIF1ATP53 | |
| SCHEMBL3266492 | 0.79 | CES1 (0.65) | CES1TSHRALDH1A1AKT1TDP1 | |
| SCHEMBL9860776 | 0.79 | CES1 (0.64) | CES1TSHRALDH1A1HIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0456040-A1 | Copolymerisable photoinitiators of the benzil ketal type | CIBA-GEIGY AG (CH) | 1991-11-13 | — | — | EP | disclosed |