Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.42 |
| ▸ | CA2 | P00918 | 5/20 | 0.42 |
| ▸ | CA9 | Q16790 | 5/20 | 0.42 |
| ▸ | CA1 | P00915 | 4/20 | 0.42 |
| ▸ | CA4 | P22748 | 4/20 | 0.42 |
| ▸ | CA7 | P43166 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | GPR3 | P46089 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6796058 | 0.84 | CA12 (0.43) | CA12CA2CA9CA1CA4 | |
| SCHEMBL7190117 | 0.84 | CA12 (0.43) | CA12CA2CA9CA1CA4 | |
| Hydrochloric Acid SCHEMBL3809667 | 0.83 | CA12 (0.42) | CA12CA2CA9CA1CA4 | |
| SCHEMBL7973834 | 0.82 | SLC40A1 (0.40) | CA12CA2CA9CA1CA4 | |
| SCHEMBL30218281 | 0.79 | CA12 (0.39) | CA12CA2CA9CA1CA4 | |
| SCHEMBL11701964 | 0.79 | SLC40A1 (0.40) | CA12CA2CA9CA1CA4 | |
| Methane SCHEMBL11040703 | 0.75 | CA12 (0.39) | CA12CA2CA9CA1CA4 | |
| SCHEMBL11090515 | 0.74 | CA12 (0.42) | CA12CA2CA9CA1CA4 | |
| SCHEMBL19138045 | 0.73 | PTGES (0.55) | CA12CA2CA9CA7KMT2A | |
| SCHEMBL11002885 | 0.73 | CA12 (0.49) | CA12CA2CA9CA1CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413051-A1 | Benzothiazine-1,1-dioxide derivatives | NIPPON HYPOX LABORATORIES INCORPORATED (JP) | 1991-02-20 | — | — | EP | disclosed |