Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9849065 | 0.90 | PLAU (0.34) | PLAUSLC22A12 | |
| SCHEMBL9849202 | 0.76 | PLAU (0.40) | PLAU | |
| SCHEMBL9849208 | 0.75 | GRIN2D (0.39) | PLAUSLC22A12 | |
| SCHEMBL9849300 | 0.70 | CYP19A1 (0.44) | — | |
| SCHEMBL9849204 | 0.68 | PLAU (0.40) | PLAU | |
| SCHEMBL23088349 | 0.67 | USP8 (0.44) | — | |
| SCHEMBL28518453 | 0.67 | USP8 (0.44) | — | |
| SCHEMBL29792782 | 0.67 | USP8 (0.44) | — | |
| SCHEMBL30576360 | 0.65 | KDM4E (0.36) | — | |
| SCHEMBL15124651 | 0.65 | KDM4E (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0421436-A2 | Substituted carboxytetrahydroisoquinolines and derivatives thereof having pharmaceutical activity | WARNER-LAMBERT COMPANY (US) | 1991-04-10 | — | — | EP | claimed |
| EP-0421436-A2 | Substituted carboxytetrahydroisoquinolines and derivatives thereof having pharmaceutical activity | WARNER-LAMBERT COMPANY (US) | 1991-04-10 | — | — | EP | disclosed |