Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 4/20 | 0.32 |
| ▸ | CASP3 | P42574 | 4/20 | 0.32 |
| ▸ | CASP7 | P55210 | 4/20 | 0.32 |
| ▸ | CASP6 | P55212 | 4/20 | 0.32 |
| ▸ | CASP8 | Q14790 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9849056 | 0.94 | MAOB (0.32) | MAOBCASP1CASP3CASP7CASP6 | |
| SCHEMBL9780082 | 0.91 | MAOB (0.34) | MAOBCASP1CASP3CASP7CASP6 | |
| SCHEMBL9026625 | 0.83 | — | — | |
| SCHEMBL9849073 | 0.83 | CASP1 (0.37) | MAOBCASP1CASP3CASP7CASP6 | |
| SCHEMBL9026617 | 0.83 | — | — | |
| SCHEMBL9027154 | 0.78 | — | — | |
| SCHEMBL9027167 | 0.78 | — | — | |
| SCHEMBL9571397 | 0.78 | NR3C1 (0.34) | — | |
| SCHEMBL9571399 | 0.78 | TSHR (0.34) | IDO1 | |
| SCHEMBL9849041 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445827-A2 | 4-Hydroxytetrahydropyran-2-one derivatives useful as cholesterol and lipid reducing agents | FUJIREBIO INC. (JP) | 1991-09-11 | — | — | EP | claimed |
| EP-0445827-A2 | 4-Hydroxytetrahydropyran-2-one derivatives useful as cholesterol and lipid reducing agents | FUJIREBIO INC. (JP) | 1991-09-11 | — | — | EP | disclosed |