Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 2/20 | 0.33 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 4/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | PLAT | P00750 | 1/20 | 0.30 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9849177 | 0.88 | CACNA2D1 (0.43) | CACNA2D1KDM4EALDH1A1POLBMALT1 | |
| SCHEMBL754037 | 0.77 | PLAU (0.50) | CACNA2D1KDM4EALDH1A1POLBPLAU | |
| SCHEMBL9849291 | 0.74 | PLAU (0.39) | KDM4EPLAUELANEPLAT | |
| SCHEMBL7435730 | 0.74 | KMT2A (0.56) | CACNA2D1POLBELANE | |
| SCHEMBL7438690 | 0.72 | KDM4E (0.44) | CACNA2D1KDM4EALDH1A1POLBELANE | |
| SCHEMBL27314484 | 0.70 | KDM4E (0.47) | KDM4EALDH1A1POLBMALT1ELANE | |
| SCHEMBL9849240 | 0.69 | POLB (0.39) | CACNA2D1KDM4EALDH1A1POLBMALT1 | |
| SCHEMBL20292623 | 0.68 | KDM4E (0.44) | CACNA2D1KDM4EALDH1A1POLBMALT1 | |
| SCHEMBL3939571 | 0.68 | ALDH1A1 (0.48) | CACNA2D1KDM4EALDH1A1POLB | |
| SCHEMBL4856952 | 0.68 | PLAU (0.46) | CACNA2D1KDM4EALDH1A1POLBPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0421436-A2 | Substituted carboxytetrahydroisoquinolines and derivatives thereof having pharmaceutical activity | WARNER-LAMBERT COMPANY (US) | 1991-04-10 | — | — | EP | disclosed |