SCHEMBL984932

SCHEMBL984932

NC(=O)c1ccc2c(c1)C1(OC2=O)c2ccc(O)cc2Oc2cc(O)ccc21

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FTO Q9C0B1 10/20 0.66
MAPT P10636 4/20 0.66
MEN1 O00255 3/20 0.66
KMT2A Q03164 3/20 0.66
HPGD P15428 2/20 0.66
HTT P42858 2/20 0.66
TDP1 Q9NUW8 2/20 0.66
CYP2C19 P33261 1/20 0.66
RECQL P46063 1/20 0.66
BLM P54132 1/20 0.66
SMAD3 P84022 1/20 0.66
PRMT1 Q99873 1/20 0.66
ACE2 Q9BYF1 1/20 0.66
ALDH1A1 P00352 3/20 0.47
ALOX12 P18054 2/20 0.47
ALOX15 P16050 2/20 0.47
HSD17B10 Q99714 2/20 0.47
CYP2C9 P11712 1/20 0.47
BRCA1 P38398 1/20 0.47
LMNA P02545 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29537895 1.00 FTO (0.66) FTOMAPTMEN1KMT2AHPGD
SCHEMBL15059064 0.91 FTO (0.70) FTOMAPTMEN1KMT2AHPGD
SCHEMBL29995323 0.91 FTO (0.70) FTOMAPTMEN1KMT2AHPGD
SCHEMBL20833 0.89 FTO (0.67) FTOMAPTMEN1KMT2AHPGD
SCHEMBL29613006 0.89 FTO (0.67) FTOMAPTMEN1KMT2AHPGD
SCHEMBL29353864 0.89 FTO (0.67) FTOMAPTMEN1KMT2AHPGD
Water SCHEMBL25244476 0.88 FTO (0.66) FTOMAPTMEN1KMT2AHPGD
SCHEMBL14604845 0.88 FTO (0.66) FTOMAPTMEN1KMT2AHPGD
Ammonia Solution, Strong SCHEMBL29083295 0.88 FTO (0.66) FTOMAPTMEN1KMT2AHPGD
SCHEMBL27907992 0.88 FTO (0.66) FTOMAPTMEN1KMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024123836-A1 IMMUNE-ACTIVATING COMPLEXES DYNAMIC CELL THERAPIES, INC. (US) 2024-06-13 WO claimed
WO-2024123835-A1 ENGINEERED SWITCHES FOR IMMUNE CELL ACTIVITY AND METHODS OF USE THEREOF DYNAMIC CELL THERAPIES, INC. (US) 2024-06-13 WO claimed
WO-2024123836-A1 IMMUNE-ACTIVATING COMPLEXES DYNAMIC CELL THERAPIES, INC. (US) 2024-06-13 WO disclosed
WO-2024123835-A1 ENGINEERED SWITCHES FOR IMMUNE CELL ACTIVITY AND METHODS OF USE THEREOF DYNAMIC CELL THERAPIES, INC. (US) 2024-06-13 WO disclosed
US-20140023592-A1 SELF COUPLING RECOMBINANT ANTIBODY FUSION PROTEINS RWTH AACHEN (DE) 2014-01-23 US disclosed
EP-2587263-A1 Self coupling recombinant antibody fusion proteins Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2013-05-01 EP disclosed
US-20110014196-A1 Drug Transfer into Living Cells COVALYS BIOSCIENCES AG (CH) 2011-01-20 US disclosed
US-20100183516-A1 SELF COUPLING RECOMBINANT ANTIBODY FUSION PROTEINS FRAUNHOFER-GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) 2010-07-22 US disclosed
EP-2171456-A2 SELF COUPLING RECOMBINANT ANTIBODY FUSION PROTEINS Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2010-04-07 EP disclosed
WO-2009043899-A1 DRUG TRANSFER INTO LIVING CELLS COVALYS BIOSCIENCES AG (CH) 2009-04-09 WO disclosed
WO-2009013359-A2 SELF COUPLING RECOMBINANT ANTIBODY FUSION PROTEINS FRAUNHOFER GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDTEN FORSCHUNG E. V. (DE) 2009-01-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110014196-A1 Drug Transfer into Living Cells TSPO, MPI, ABCB1 FTO 1922/4885MAPT 237/4885MEN1 506/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.