Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 2/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 3/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9849379 | 0.87 | MMP3 (0.46) | MMP3ENPP2FFAR1MEN1KMT2A | |
| SCHEMBL29068855 | 0.81 | FFAR1 (0.50) | FFAR1FFAR4LMNA | |
| SCHEMBL9849212 | 0.78 | CYP4F2 (0.36) | F2 | |
| SCHEMBL9849186 | 0.77 | TAAR1 (0.55) | LMNA | |
| SCHEMBL237972 | 0.76 | ENPP2 (0.63) | MMP3ENPP2FFAR1MEN1KMT2A | |
| Butane SCHEMBL5301919 | 0.75 | BCL2 (0.37) | TDP1F2MAPT | |
| SCHEMBL29149475 | 0.75 | IDO1 (0.55) | — | |
| SCHEMBL27850575 | 0.75 | CYP19A1 (0.47) | TDP1 | |
| SCHEMBL27370550 | 0.75 | IDO1 (0.55) | FFAR1FFAR4 | |
| Benzene SCHEMBL5438521 | 0.74 | ENPP2 (0.61) | MMP3ENPP2FFAR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0421436-A2 | Substituted carboxytetrahydroisoquinolines and derivatives thereof having pharmaceutical activity | WARNER-LAMBERT COMPANY (US) | 1991-04-10 | — | — | EP | disclosed |