Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 4/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9849441 | 0.88 | OPRL1 (0.35) | OPRL1OPRM1OPRK1HDAC4OPRD1 | |
| SCHEMBL731689 | 0.85 | HDAC4 (0.35) | OPRL1OPRM1OPRK1HDAC4OPRD1 | |
| SCHEMBL731291 | 0.81 | HDAC4 (0.40) | OPRL1OPRM1OPRK1HDAC4OPRD1 | |
| SCHEMBL9346748 | 0.77 | OPRM1 (0.34) | OPRL1OPRM1OPRK1MAPTOPRD1 | |
| SCHEMBL9015153 | 0.76 | HDAC4 (0.35) | OPRL1OPRM1OPRK1HDAC4OPRD1 | |
| SCHEMBL1574519 | 0.73 | HDAC4 (0.38) | HDAC4 | |
| SCHEMBL12733562 | 0.71 | HDAC4 (0.42) | OPRL1OPRM1OPRK1HDAC4OPRD1 | |
| SCHEMBL1574708 | 0.70 | PSEN1 (0.32) | OPRL1HDAC4 | |
| SCHEMBL8643261 | 0.69 | HDAC4 (0.40) | OPRL1OPRM1OPRK1HDAC4MAPT | |
| SCHEMBL8643255 | 0.69 | HDAC4 (0.40) | OPRL1OPRM1OPRK1HDAC4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0423926-A1 | Difluorobenzonitrile derivatives | Chisso Corporation (JP) | 1991-04-24 | — | — | EP | disclosed |