Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TOP2A | P11388 | 1/20 | 0.31 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11032370 | 0.83 | CRBN (0.35) | CRBN | |
| SCHEMBL5598731 | 0.78 | CRBN (0.43) | CRBNALDH1A1TOP2ATOP2BMAPT | |
| SCHEMBL8880520 | 0.70 | — | — | |
| SCHEMBL9849560 | 0.70 | — | — | |
| SCHEMBL8699047 | 0.70 | — | — | |
| SCHEMBL8692835 | 0.68 | CRBN (0.41) | CRBNALDH1A1TOP2ATOP2BMAPT | |
| SCHEMBL11420842 | 0.64 | ALDH1A1 (0.40) | ALDH1A1LMNATP53CYP3A4HPGD | |
| SCHEMBL6413982 | 0.64 | CRBN (0.41) | CRBNALDH1A1LMNATOP2ATOP2B | |
| SCHEMBL10531811 | 0.64 | CRBN (0.41) | CRBNALDH1A1TOP2ATOP2BMAPT | |
| SCHEMBL11583227 | 0.63 | TOP2A (0.42) | CRBNALDH1A1LMNATOP2ATOP2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-87102449-A | The application of composition in vulcanizable rubber stock of the N-trichloromethyl thiohydantoin that replaces and two (2,4-diamino-S-triazinyl-6)-protosulphides and this class rubber stock | — | 1987-10-14 | — | — | CN | claimed |
| EP-0427942-A2 | Process for the preparation of s-triazine-sulfenimides and their use | Degussa Aktiengesellschaft (DE) | 1991-05-22 | — | — | EP | disclosed |
| CN-1010952-B | Use of substituted N-trichloromethyl thiohydantoins in combination with bis (2, 4-diamino-S-triazin-6-yl) -oligosulfides in vulcanizable rubber mixtures and rubber mixtures of this type | DEGUSSA (DE) | 1990-12-26 | — | — | CN | disclosed |
| CN-87102449-A | The application of composition in vulcanizable rubber stock of the N-trichloromethyl thiohydantoin that replaces and two (2,4-diamino-S-triazinyl-6)-protosulphides and this class rubber stock | — | 1987-10-14 | — | — | CN | disclosed |
| CN-87102449-A | The application of composition in vulcanizable rubber stock of the N-trichloromethyl thiohydantoin that replaces and two (2,4-diamino-S-triazinyl-6)-protosulphides and this class rubber stock | — | 1987-10-14 | — | — | CN | disclosed |
| CN-87102449-A | The application of composition in vulcanizable rubber stock of the N-trichloromethyl thiohydantoin that replaces and two (2,4-diamino-S-triazinyl-6)-protosulphides and this class rubber stock | — | 1987-10-14 | — | — | CN | disclosed |
| EP-0239813-A2 | Use of substituted N-trichloromethylthiohydantoins in combination with bis-(2,4-diamino-s-triazin-6-yl)-oligosulfides in vulcanizable rubber compositions, and such rubber compositions | Degussa Aktiengesellschaft (DE) | 1987-10-07 | — | — | EP | disclosed |
| EP-0239813-A2 | Use of substituted N-trichloromethylthiohydantoins in combination with bis-(2,4-diamino-s-triazin-6-yl)-oligosulfides in vulcanizable rubber compositions, and such rubber compositions | Degussa Aktiengesellschaft (DE) | 1987-10-07 | — | — | EP | disclosed |
| EP-0239813-A2 | Use of substituted N-trichloromethylthiohydantoins in combination with bis-(2,4-diamino-s-triazin-6-yl)-oligosulfides in vulcanizable rubber compositions, and such rubber compositions | Degussa Aktiengesellschaft (DE) | 1987-10-07 | — | — | EP | disclosed |