Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.52 |
| ▸ | MEN1 | O00255 | 6/20 | 0.52 |
| ▸ | PABPC1 | P11940 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10482836 | 0.82 | KMT2A (0.51) | KDM4EKMT2AMEN1PABPC1MAPT | |
| SCHEMBL41767 | 0.82 | KMT2A (0.58) | KDM4EKMT2AMEN1PABPC1MAPT | |
| SCHEMBL6846376 | 0.79 | KMT2A (0.58) | KDM4EKMT2AMEN1PABPC1MAPT | |
| SCHEMBL10417850 | 0.79 | KMT2A (0.58) | KDM4EKMT2AMEN1PABPC1MAPT | |
| Cyclopropane SCHEMBL8126236 | 0.78 | NPC1 (0.56) | KDM4EKMT2AMEN1PABPC1MAPT | |
| SCHEMBL2397341 | 0.78 | RAB9A (0.58) | KDM4EKMT2AMEN1PABPC1MAPT | |
| SCHEMBL4130196 | 0.75 | HTT (0.54) | KDM4EKMT2AMEN1PABPC1MAPT | |
| SCHEMBL10416677 | 0.75 | KDM4E (0.57) | KDM4EKMT2AMEN1PABPC1MAPT | |
| SCHEMBL27954442 | 0.74 | KDM4E (0.71) | KDM4EKMT2AMEN1PABPC1MAPT | |
| SCHEMBL5299753 | 0.74 | KMT2A (0.50) | KDM4EKMT2AMEN1PABPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0434357-A2 | Fungicides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-06-26 | — | — | EP | disclosed |
| US-4895858-A | Fungicidal pyridyl cyclopropane carboxamides | ICI AMERICAS INC. (US) | 1990-01-23 | — | — | US | disclosed |
| US-4808600-A | Fungicidal pyridyl cyclopropane carboxamides | STAUFFER CHEMICAL CO. (US) | 1989-02-28 | — | — | US | disclosed |
| US-4766134-A | Fungicidal pyridyl cyclopropane carboxamides | STAUFFER CHEMICAL CO. (US) | 1988-08-23 | — | — | US | disclosed |
| EP-0243971-A2 | Fungicidal pyridyl cyclopropane carboxamides | STAUFFER CHEMICAL COMPANY (US) | 1987-11-04 | — | — | EP | disclosed |