Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 10/20 | 0.47 |
| ▸ | RAB9A | P51151 | 10/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | AGER | Q15109 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MITF | O75030 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11679738 | 0.78 | SMN1; SMN2 (0.51) | L3MBTL1KMT2ASMN1; SMN2GAANPC1 | |
| SCHEMBL29844261 | 0.76 | MCL1 (0.48) | L3MBTL1KMT2ASMN1; SMN2GAANPC1 | |
| SCHEMBL1799259 | 0.75 | ALDH1A1 (0.45) | KMT2ASMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL22514066 | 0.74 | MCL1 (0.47) | L3MBTL1KMT2ASMN1; SMN2GAANPC1 | |
| SCHEMBL1017987 | 0.74 | MCL1 (0.61) | L3MBTL1KMT2ASMN1; SMN2GAANPC1 | |
| SCHEMBL9102881 | 0.73 | HPGD (0.48) | L3MBTL1KMT2ASMN1; SMN2GAANPC1 | |
| SCHEMBL8579443 | 0.72 | NPC1 (0.44) | L3MBTL1KMT2ASMN1; SMN2GAANPC1 | |
| SCHEMBL1796296 | 0.72 | LMNA (0.41) | L3MBTL1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL9790177 | 0.71 | CA12 (0.50) | L3MBTL1KMT2ASMN1; SMN2GAANPC1 | |
| SCHEMBL2257900 | 0.70 | ALDH1A1 (0.45) | L3MBTL1KMT2ASMN1; SMN2GAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0418175-A2 | Isoxazoles herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1991-03-20 | — | — | EP | disclosed |