Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4A11 | Q02928 | 6/20 | 0.53 |
| ▸ | CYP4F2 | P78329 | 5/20 | 0.47 |
| ▸ | DAO | P14920 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.38 |
| ▸ | CTPS1 | P17812 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1604772 | 0.95 | CYP4A11 (0.54) | CYP4A11CYP4F2DAONPSR1MAPT | |
| SCHEMBL9849871 | 0.94 | CYP4A11 (0.53) | CYP4A11CYP4F2DAONPSR1MAPT | |
| SCHEMBL9850003 | 0.90 | CYP4A11 (0.49) | CYP4A11CYP4F2DAONPSR1MAPT | |
| SCHEMBL28342951 | 0.86 | DAO (0.44) | CYP4A11CYP4F2DAONPSR1MAPT | |
| SCHEMBL12468480 | 0.84 | DAO (0.46) | CYP4A11DAONPSR1MAPTMAPK1 | |
| SCHEMBL8226496 | 0.83 | DAO (0.47) | CYP4A11CYP4F2DAONPSR1MAPT | |
| SCHEMBL18152974 | 0.83 | MAPT (0.39) | CYP4A11CYP4F2DAONPSR1MAPT | |
| SCHEMBL1401548 | 0.83 | NPSR1 (0.47) | CYP4A11CYP4F2DAONPSR1MAPT | |
| SCHEMBL6618423 | 0.82 | DAO (0.46) | CYP4A11CYP4F2DAONPSR1MAPT | |
| SCHEMBL8180294 | 0.81 | NPSR1 (0.48) | DAONPSR1MAPTCTPS1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415510-A2 | L-glutamic acid derivatives | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1991-03-06 | — | — | EP | disclosed |
| US-4920125-A | L-glutamic acid derivatives | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1990-04-24 | — | — | US | disclosed |