Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4A11 | Q02928 | 5/20 | 0.53 |
| ▸ | CYP4F2 | P78329 | 4/20 | 0.53 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | LTB4R | Q15722 | 4/20 | 0.36 |
| ▸ | CES1 | P23141 | 3/20 | 0.36 |
| ▸ | CTPS1 | P17812 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1604772 | 0.98 | CYP4A11 (0.54) | CYP4A11CYP4F2DAOMAPTNPSR1 | |
| SCHEMBL9849635 | 0.94 | CYP4A11 (0.53) | CYP4A11CYP4F2DAOMAPTNPSR1 | |
| SCHEMBL9850003 | 0.87 | CYP4A11 (0.49) | CYP4A11CYP4F2DAOMAPTNPSR1 | |
| SCHEMBL28342951 | 0.83 | DAO (0.44) | CYP4A11CYP4F2DAOMAPTNPSR1 | |
| SCHEMBL12468480 | 0.82 | DAO (0.46) | CYP4A11DAOMAPTNPSR1LTB4R | |
| SCHEMBL9849709 | 0.81 | LMNA (0.39) | CYP4A11CYP4F2DAOMAPTNPSR1 | |
| SCHEMBL8226496 | 0.81 | DAO (0.47) | CYP4A11CYP4F2DAOMAPTNPSR1 | |
| SCHEMBL1401548 | 0.80 | NPSR1 (0.47) | CYP4A11CYP4F2DAOMAPTNPSR1 | |
| SCHEMBL6618423 | 0.80 | DAO (0.46) | CYP4A11CYP4F2DAOMAPTNPSR1 | |
| SCHEMBL9849602 | 0.79 | KDM4E (0.40) | CYP4A11CYP4F2DAOMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415510-A2 | L-glutamic acid derivatives | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1991-03-06 | — | — | EP | disclosed |
| US-4920125-A | L-glutamic acid derivatives | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1990-04-24 | — | — | US | disclosed |