Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9849619 | 0.86 | DHFR (0.33) | CYP2D6DHFR | |
| SCHEMBL9849759 | 0.78 | FOLR1 (0.44) | CYP2D6DHFR | |
| SCHEMBL9850018 | 0.77 | FOLR1 (0.43) | CYP2D6DHFR | |
| SCHEMBL9849823 | 0.76 | CYP2D6 (0.37) | CYP2D6DHFR | |
| SCHEMBL9849753 | 0.75 | FOLR1 (0.47) | CYP2D6DHFR | |
| SCHEMBL9849821 | 0.74 | DAO (0.44) | CYP2D6DHFR | |
| SCHEMBL9338914 | 0.71 | CYP2D6 (0.56) | CYP2D6DHFR | |
| SCHEMBL9343568 | 0.70 | CYP2D6 (0.55) | CYP2D6DHFR | |
| SCHEMBL9343727 | 0.70 | CYP2D6 (0.42) | CYP2D6DHFR | |
| SCHEMBL9849814 | 0.70 | CYP2D6 (0.38) | CYP2D6DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415510-A2 | L-glutamic acid derivatives | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1991-03-06 | — | — | EP | disclosed |
| US-4920125-A | L-glutamic acid derivatives | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1990-04-24 | — | — | US | disclosed |