Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | PRCP | P42785 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9448102 | 0.81 | PRCP (0.51) | SIGMAR1PRCPCYP11B2 | |
| SCHEMBL9447973 | 0.75 | SLC22A1 (0.43) | PDPK1PRCP | |
| SCHEMBL9121299 | 0.71 | DRD1 (0.49) | SIGMAR1PDPK1DRD2PRCP | |
| SCHEMBL9121303 | 0.71 | DRD1 (0.49) | SIGMAR1PDPK1DRD2PRCP | |
| SCHEMBL8168607 | 0.71 | DRD1 (0.49) | SIGMAR1PDPK1DRD2PRCP | |
| SCHEMBL29547256 | 0.69 | BCHE (0.56) | HTR1APDPK1DRD2 | |
| SCHEMBL4431417 | 0.69 | BCHE (0.56) | HTR1APDPK1DRD2 | |
| SCHEMBL1009943 | 0.68 | PRCP (0.64) | PRCP | |
| SCHEMBL9447918 | 0.68 | SLC22A1 (0.49) | SIGMAR1PDPK1PRCPCYP11B2 | |
| SCHEMBL11671198 | 0.65 | SRD5A1 (0.55) | HTR1ASIGMAR1PDPK1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0410535-A2 | Octahydrobenzisoquinoline derivatives as antipsychotic agents | MERCK SHARP & DOHME LTD. (GB) | 1991-01-30 | — | — | EP | disclosed |