Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 2/20 | 0.51 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9447973 | 0.91 | SLC22A1 (0.43) | PRCPSLC22A1GAA | |
| SCHEMBL9447918 | 0.87 | SLC22A1 (0.49) | PRCPSLC22A1CYP11B2SIGMAR1HTR6 | |
| SCHEMBL9448327 | 0.82 | NPY5R (0.48) | SIGMAR1 | |
| SCHEMBL9849844 | 0.81 | HTR1A (0.43) | PRCPCYP11B2SIGMAR1 | |
| SCHEMBL9447923 | 0.78 | SLC22A1 (0.43) | PRCPSLC22A1CYP11B2SIGMAR1HTR6 | |
| SCHEMBL9447914 | 0.78 | SLC22A1 (0.43) | PRCPSLC22A1CYP11B2SIGMAR1HTR6 | |
| SCHEMBL9447970 | 0.78 | SLC22A1 (0.43) | PRCPSLC22A1CYP11B2SIGMAR1HTR6 | |
| Hydrochloric Acid SCHEMBL9448342 | 0.77 | SLC22A1 (0.42) | PRCPSLC22A1CYP11B2SIGMAR1HTR6 | |
| SCHEMBL9448312 | 0.77 | PRCP (0.42) | PRCPSLC22A1CYP11B2SIGMAR1HTR6 | |
| Hydrochloric Acid SCHEMBL9448436 | 0.77 | SLC22A1 (0.42) | PRCPSLC22A1CYP11B2SIGMAR1HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5248677-A | Nervous system disorders or antidepressants | ABBOTT LABORATORIES (US) | 1993-09-28 | — | — | US | disclosed |
| US-5180733-A | Antidepressants or nervous systen disorders | ABBOTT LABORATORIES (US) | 1993-01-19 | — | — | US | disclosed |