Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 4/20 | 0.71 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.71 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25658 | 1.00 | CHRNA7 (0.71) | CHRNA7CHRNB2CHRNA4ALDH1A1CHRNA1 | |
| Hydrochloric Acid SCHEMBL6154466 | 0.98 | CHRNB2 (0.69) | CHRNA7CHRNB2CHRNA4ALDH1A1CHRNA1 | |
| SCHEMBL16592137 | 0.79 | CHRNB2 (0.68) | CHRNA7CHRNB2CHRNA4ALDH1A1 | |
| SCHEMBL4681435 | 0.78 | CHRNB2 (0.45) | CHRNA7CHRNB2CHRNA4ALDH1A1 | |
| SCHEMBL9041158 | 0.75 | CHRNB2 (0.62) | CHRNA7CHRNB2CHRNA4ALDH1A1 | |
| SCHEMBL160708 | 0.67 | CHRNB2 (1.00) | CHRNA7CHRNB2CHRNA4ALDH1A1CHRNA1 | |
| SCHEMBL13589890 | 0.67 | CHRNB2 (1.00) | CHRNA7CHRNB2CHRNA4ALDH1A1CHRNA1 | |
| SCHEMBL21307962 | 0.67 | CHRNB2 (1.00) | CHRNA7CHRNB2CHRNA4ALDH1A1CHRNA1 | |
| SCHEMBL29484643 | 0.67 | CHRNB2 (1.00) | CHRNA7CHRNB2CHRNA4ALDH1A1CHRNA1 | |
| Fumaric Acid SCHEMBL29615612 | 0.64 | CHRNB2 (0.82) | CHRNA7CHRNB2CHRNA4ALDH1A1CHRNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445731-A1 | Azabicyclo and azacyclo oxime and amine cholinergic agents and pharmaceutically acceptable salts thereof | WARNER-LAMBERT COMPANY (US) | 1991-09-11 | — | — | EP | disclosed |