SCHEMBL25658

SCHEMBL25658

O=C(O)C1=CC[C@@H]2CC[C@H]1N2

nearest known ligand 0.71

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CHRNA7 P36544 4/20 0.71
CHRNB2 P17787 3/20 0.71
CHRNA4 P43681 3/20 0.71
ALDH1A1 P00352 1/20 0.50
CHRNA1 P02708 1/20 0.31
CHRNB4 P30926 1/20 0.31
CHRNA3 P32297 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9849965 1.00 CHRNA7 (0.71) CHRNA7CHRNB2CHRNA4ALDH1A1CHRNA1
Hydrochloric Acid SCHEMBL6154466 0.98 CHRNB2 (0.69) CHRNA7CHRNB2CHRNA4ALDH1A1CHRNA1
SCHEMBL16592137 0.79 CHRNB2 (0.68) CHRNA7CHRNB2CHRNA4ALDH1A1
SCHEMBL4681435 0.78 CHRNB2 (0.45) CHRNA7CHRNB2CHRNA4ALDH1A1
SCHEMBL9041158 0.75 CHRNB2 (0.62) CHRNA7CHRNB2CHRNA4ALDH1A1
SCHEMBL160708 0.67 CHRNB2 (1.00) CHRNA7CHRNB2CHRNA4ALDH1A1CHRNA1
SCHEMBL13589890 0.67 CHRNB2 (1.00) CHRNA7CHRNB2CHRNA4ALDH1A1CHRNA1
SCHEMBL21307962 0.67 CHRNB2 (1.00) CHRNA7CHRNB2CHRNA4ALDH1A1CHRNA1
SCHEMBL29484643 0.67 CHRNB2 (1.00) CHRNA7CHRNB2CHRNA4ALDH1A1CHRNA1
Fumaric Acid SCHEMBL29615612 0.64 CHRNB2 (0.82) CHRNA7CHRNB2CHRNA4ALDH1A1CHRNA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1454 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260115156-A1 INJECTABLE COMPOSITION INCLUDING HYDROGEL CONTAINING ANESTHETIC AGENT UNIV KOREA RES & BUS FOUND (KR) 2026-04-30 US claimed
WO-2025235864-A1 COATED NEEDLE ADMINISTRATION SYSTEMS EVOLUS, INC. (US) 2025-11-13 WO claimed
US-12329856-B2 Crosslinked hyaluronic acid composition with local anesthetics BIOPOLIMERI S.R.L. (IT) 2025-06-17 US claimed
US-20250186364-A1 COMBINATION OF ANTISPASMODIC AND ANESTHETIC AGENTS FOR TOPICAL PRODUCTS AND THEIR METHOD OF USE PRIMA INNOVATIONS, LLC 2025-06-12 US claimed
EP-4362994-B1 CROSSLINKED HYALURONIC ACID COMPOSITION WITH LOCAL ANESTHETICS BIOPOLIMERI S R L (IT) 2025-03-12 EP claimed
EP-3703802-B9 NASAL DELIVERY DEVICES AND METHODS OF USE THEREOF CLEXIO BIOSCIENCES LTD (IL) 2024-12-04 EP claimed
EP-3703802-B1 NASAL DELIVERY DEVICES AND METHODS OF USE THEREOF CLEXIO BIOSCIENCES LTD (IL) 2024-10-16 EP claimed
US-20240293311-A1 CROSSLINKED HYALURONIC ACID COMPOSITION WITH LOCAL ANESTHETICS BIOPOLIMERI S.R.L. (IT) 2024-09-05 US claimed
US-20240261464-A1 POWDER FORMULATION FOR TISSUE REPAIR, PREPARATION METHOD THEREFOR, AND INJECTABLE COMPOSITION FOR TISSUE REPAIR, COMPRISING SAME SAMYANG HOLDINGS CORPORATION (KR) 2024-08-08 US claimed
EP-4374885-A1 POWDER FORMULATION FOR TISSUE REPAIR, PREPARATION METHOD THEREFOR, AND INJECTABLE COMPOSITION FOR TISSUE REPAIR, COMPRISING SAME Samyang Holdings Corporation (KR) 2024-05-29 EP claimed
US-5663345-A Derivatives of benzoylecgonine, ecgonine and ecgonidine and methods for preparing and using same ENTROPIN, INC. (US) 1997-09-02 US claimed
CN-1150802-A Benzoylecgonine, ecgonine and ecgonidine derivatives ENTROPIN INC (US) 1997-05-28 CN claimed
EP-0765326-A1 BENZOYLECGONINE, ECGONINE AND ECGONIDINE DERIVATIVES ENTROPIN, INC. (US) 1997-04-02 EP claimed
US-5559123-A Derivatives of benzoylecgonine, ecgonine and ecgonidine and methods for preparing and using same ENTROPIN, INC. (US) 1996-09-24 US claimed
US-5525613-A Covalently coupled benzoylecgonine ecgonine and ecgonidine ENTROPIN, INC. (US) 1996-06-11 US claimed
WO-1995034561-A1 BENZOYLECGONINE, ECGONINE AND ECGONIDINE DERIVATIVES ENTROPIN, INC. (US) 1995-12-21 WO claimed
EP-0677051-A1 DERIVATIVES OF BENZOYLECGONINE, ECGONINE AND ECGONIDINE AS MEDICINES ENTROPIN, INC. (US) 1995-10-18 EP claimed
US-5376667-A Derivatives of benzoylecgonine, ecgonine and their multiple pharmacological properties ENTROPIN, INC. (US) 1994-12-27 US claimed
CN-1095720-A The benzoyl tropine carboxylic acid, their method of the derivative of tropine carboxylic acid and ecgonidine and preparation thereof and use ENTROPIN INC (US) 1994-11-30 CN claimed
WO-1994015935-A1 DERIVATIVES OF BENZOYLECGONINE, ECGONINE AND ECGONIDINE AS MEDICINES ENTROPIN, INC. (US) 1994-07-21 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12329856-B2 Crosslinked hyaluronic acid composition with local anesthetics CD44, HCAR3, HCAR2 CHRNA7 1046/4885CHRNB2 1953/4885CHRNA4 1198/4885
US-20260115156-A1 INJECTABLE COMPOSITION INCLUDING HYDROGEL CONTAINING ANESTHETIC AGENT CES2, DAGLA, ACHE CHRNA7 47/4885CHRNB2 50/4885CHRNA4 33/4885
US-20240293311-A1 CROSSLINKED HYALURONIC ACID COMPOSITION WITH LOCAL ANESTHETICS CD44, HCAR3, HCAR2 CHRNA7 1046/4885CHRNB2 1953/4885CHRNA4 1198/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.