Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 9/20 | 0.64 |
| ▸ | RARB | P10826 | 9/20 | 0.64 |
| ▸ | RXRA | P19793 | 6/20 | 0.55 |
| ▸ | HNF4A | P41235 | 2/20 | 0.55 |
| ▸ | RARG | P13631 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | RXRG | P48443 | 3/20 | 0.41 |
| ▸ | RXRB | P28702 | 2/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | ACR | P10323 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.39 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9850096 | 0.93 | RARA (0.56) | RARARARBRXRAHNF4ARARG | |
| SCHEMBL9850185 | 0.92 | RARA (0.56) | RARARARBRXRAHNF4ARARG | |
| SCHEMBL9850125 | 0.89 | RARB (0.55) | RARARARBRXRAHNF4ARARG | |
| SCHEMBL9850221 | 0.89 | RARA (0.54) | RARARARBRXRAHNF4ARARG | |
| SCHEMBL8461526 | 0.87 | RARA (0.62) | RARARARBRXRAHNF4ARARG | |
| SCHEMBL9850240 | 0.86 | RARA (0.52) | RARARARBRXRAHNF4ARARG | |
| SCHEMBL9551743 | 0.86 | RARA (0.74) | RARARARBRXRAHNF4ARARG | |
| SCHEMBL9850253 | 0.84 | RXRA (0.49) | RARARARBRXRAHNF4ARARG | |
| SCHEMBL8460713 | 0.83 | RARA (0.58) | RARARARBRXRAHNF4ARARG | |
| SCHEMBL9850106 | 0.82 | RXRA (0.48) | RARARARBRXRAHNF4ARARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0435681-A1 | Chroman esters of phenols and benzoic acids having retinoid-like activity | ALLERGAN, INC. (US) | 1991-07-03 | — | — | EP | disclosed |
| US-5006550-A | Skin disorder, arthritis, wound healing agents, dry eye syndrome | ALLERGAN, INC. (US) | 1991-04-09 | — | — | US | disclosed |