Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 6/20 | 0.43 |
| ▸ | HNF4A | P41235 | 2/20 | 0.43 |
| ▸ | RARA | P10276 | 5/20 | 0.41 |
| ▸ | RARB | P10826 | 5/20 | 0.41 |
| ▸ | RARG | P13631 | 5/20 | 0.41 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.39 |
| ▸ | CYP26B1 | Q9NR63 | 2/20 | 0.39 |
| ▸ | RXRB | P28702 | 2/20 | 0.33 |
| ▸ | RXRG | P48443 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6668058 | 0.85 | RXRA (0.50) | RXRAHNF4ARARARARBRARG | |
| SCHEMBL6668009 | 0.82 | RXRA (0.47) | RXRAHNF4ARARARARBRARG | |
| SCHEMBL6665724 | 0.80 | RXRA (0.46) | RXRAHNF4ARARARARBRARG | |
| SCHEMBL6669480 | 0.79 | RXRA (0.45) | RXRAHNF4ARARARARBRARG | |
| SCHEMBL6665895 | 0.78 | RXRA (0.44) | RXRAHNF4ARARARARBRARG | |
| SCHEMBL6664735 | 0.77 | RXRA (0.49) | RXRAHNF4ARARARARBRARG | |
| SCHEMBL9850251 | 0.75 | RXRA (0.56) | RXRAHNF4ARARARARBRARG | |
| SCHEMBL9850143 | 0.72 | RXRA (0.53) | RXRAHNF4ARARARARBRARG | |
| SCHEMBL3260843 | 0.70 | CYP3A4 (0.50) | RXRAHNF4ARARARARBRARG | |
| SCHEMBL9850259 | 0.69 | RXRA (0.50) | RXRAHNF4ARARARARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0435681-A1 | Chroman esters of phenols and benzoic acids having retinoid-like activity | ALLERGAN, INC. (US) | 1991-07-03 | — | — | EP | disclosed |
| US-5006550-A | Skin disorder, arthritis, wound healing agents, dry eye syndrome | ALLERGAN, INC. (US) | 1991-04-09 | — | — | US | disclosed |